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Gut Research Group

Gut Research Group is a research team that is part of the University of Pisa, including Professors, Assistant Professors, Research Fellows, PhD Students, Master Students and Technicians who work together for join basic and translational research with drug development.
ABOUT

We are dedicated to better understanding the mechanisms underlying diseases

In particular, we are focused on Irritable Bowel Syndrome (IBS), Inflammatory Bowel Diseases (IBDs), drug-induced enteropathy, obesity, aging and brain disorders. We believe that the gut can represent a common root to such diseases. To study this, we have a variety of animal and cellular models to mimic the disease and realize a better treatment option. In addition, we are connected to a large patient cohorts through the Azienda Ospedaliera Universitaria Pisana (AOUP).
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Research Area

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  • Drug-induced enteropathy

  • Gut-brain axis

  • IBD

  • IBS

  • Inflammaging

  • Microbiota

  • Neuro-immunity

  • Obesity

    • TEAM

    Research Team

    We are an integrated research team that, by means of multidisciplinary approaches, studies the pathophysiological mechanisms underlying digestive and gut-linked extra digestive diseases and proposes novel therapeutical options for their management.
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    News

    Focus

    Super Sapiens Europe – III edizione della Call4Ideas Super Sapiens, in collaborazione con IREFI: 1° premio a INFLANT

    https://supersapienseurope.com/

    INFLANT – SMART MATERIALS – ITALY

    Inflant has developed a solution to reduce intestinal inflammation response while preserving the immune system’s overall action against infectious diseases.

    Inflant ha sviluppato una soluzione che permette di ridurre la risposta infiammatoria dell’intestino senza alterare l’azione complessiva del sistema immunitario contro le infezioni

    Focus

    START PITCH @Converging Skills: 1° premio a INFLANT

    https://www.unipi.it/news/a-converging-skills-2025-vince-la-salute/

    Le due start up Inflant e MolBook Pro si sono aggiudicate 20mila euro in servizi per trasformare la loro idea in impresa. La proclamazione è avvenuta il 28 maggio al termine della due giorni

    https://convergingskills.unipi.it/

     

    Focus

    XXII edizione del Premio Nazionale per l’Innovazione (PNI): 1° premio a INFLANT

    https://old.unipi.it/index.php/news/item/29182-premio-nazionale-per-l-innovazione-2024-primo-posto-per-inflant-un-progetto-per-il-trattamento-delle-malattie-croniche-intestinali

    Premio Nazionale per l’Innovazione 2024: primo posto per INFLANT, un progetto per il trattamento delle malattie croniche intestinali

     

    https://agenparl.eu/2024/12/06/comunicato-stampa-premio-nazionale-per-linnovazione-pni-2024-unito-al-primo-posto-con-inflant-rivoluzionaria-terapia-per-il-trattamento-delle-malattie-croniche-intestinal/

    COMUNICATO STAMPA – PREMIO NAZIONALE PER L’INNOVAZIONE PNI 2024, UNITO AL PRIMO POSTO CON ‘INFLANT’ RIVOLUZIONARIA TERAPIA PER IL TRATTAMENTO DELLE MALATTIE CRONICHE INTESTINALI

    Focus
    Premio Start Cup Piemonte-Valle d’Aosta 2024

    Start Cup Piemonte-Valle d’Aosta 2024: 1° premio a INFLANT

    https://www.med.unipi.it/index.php/2024/11/05/inflant-premiata-alla-start-cup-piemonte-valle-daosta-2024-un-riconoscimento-allinnovazione-terapeutica/

    INFLANT premiata alla Start Cup Piemonte-Valle d’Aosta 2024: un riconoscimento all’innovazione terapeutica

     

    http://Start Cup Piemonte Valle d’Aosta 2024: Inflant al primo posto con una rivoluzionaria terapia sull’inflammasoma | Il Mediacentre

    Start Cup Piemonte Valle d’Aosta 2024: Inflant al primo posto con una rivoluzionaria terapia sull’inflammasoma

    Focus

    THE GUT BARRIER: a novel frontier in digestive and extra-digestive diseases

    Focus

    Primo congresso nazionale sulla barriera intestinale come nuova frontiera nelle malattie digestive ed extra-digestive – 2024

    SAVE THE DATE: 4-5 luglio 2024, Camera di Commercio, Pisa

     

     

     

     

    Focus

    The intestinal barrier in disorders of the central nervous system

    Our review article:’ The intestinal barrier in disorders of the central nervous system. Lancet Gastroenterol Hepatol. 2023 Jan;8(1):66-80. doi: 10.1016/S2468-1253(22)00241-2. has been selected to be the subject of Cover Illustration for January issue on LANCET GASTROENTEROLOGY AND HEPATOLOGY JOURNAL

    Gut research group - Via Roma 55, 56126, Pisa, Italy