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Gut Research Group

Gut Research Group is a research team that is part of the University of Pisa, including Professors, Assistant Professors, Research Fellows, PhD Students, Master Students and Technicians who work together for join basic and translational research with drug development.

We are dedicated to better understanding the mechanisms underlying diseases

In particular, we are focused on Irritable Bowel Syndrome (IBS), Inflammatory Bowel Diseases (IBDs), drug-induced enteropathy, obesity, aging and brain disorders. We believe that the gut can represent a common root to such diseases. To study this, we have a variety of animal and cellular models to mimic the disease and realize a better treatment option. In addition, we are connected to a large patient cohorts through the Azienda Ospedaliera Universitaria Pisana (AOUP).

Research Area


Research Team

We are an integrated research team that, by means of multidisciplinary approaches, studies the pathophysiological mechanisms underlying digestive and gut-linked extra digestive diseases and proposes novel therapeutical options for their management.


Primo congresso nazionale sulla barriera intestinale come nuova frontiera nelle malattie digestive ed extra-digestive

The intestinal barrier in disorders of the central nervous system

Our review article:’ The intestinal barrier in disorders of the central nervous system. Lancet Gastroenterol Hepatol. 2023 Jan;8(1):66-80. doi: 10.1016/S2468-1253(22)00241-2. has been selected to be the subject of Cover Illustration for January issue on LANCET GASTROENTEROLOGY AND HEPATOLOGY JOURNAL